Cardiac performance during reperfusion improved by pretreatment with oxygen free-radical scavengers
نویسندگان
چکیده
منابع مشابه
Oxygen-Derived Free Radical Generation During Ischemia and Reperfusion
It has been suggested that oxygen-derived free radicals may contribute to the myocardial injury associated with ischemia and reperfusion. As the presence of enhanced free radical generation is a prerequisite for such damage, several techniques have been used to provide evidence of increased oxygen free radical production during reperfusion; however, all such techniques have substantial limitati...
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Inducibility of sustained monomorphic ventricular tachycardia as a prognostic indicator in survivors of recent myocardial infarction: a prospective evaluation in relation to other prognostic variables. Prediction of sudden death and spontaneous ven-tricular tachycardia in survivors of uncomplicated myocardial infarction: value of the response to programmed stimulation using a maximum of three v...
متن کاملTherapeutic application of oxygen radical scavengers.
M uch of what is considered critical illness may involve oxygen radical pathophysiology.'' Data accumulated from both experimental and clinical investigations have implicated oxyradical injury in the pathogenesis of pulmonary oxygen toxicity, adult respiratory distress syndrome (ARDS), bronchopulmonary dysplasia (BPD), sepsis syndrome , and a variety of ischemia-reperfusion syndromes, including...
متن کاملQuantitative Structure Activity Relationship Analysis of Coumarins as Free Radical Scavengers by Genetic Function Algorithm
The antioxidant properties of coumarin derivatives using the 2,2ˈ -diphenyl-1- picrylhydrazyl (DPPH) radical scavenging assay were investigated by the application of Quantitative Structure Activity Relationship (QSAR) studies. The molecular structures were optimized and submitted for the generation of quantum chemical and molecular descriptors. Genetic Function Algorithm (GFA) was employed in m...
متن کاملEnhanced chemiluminescence as a measure of oxygen-derived free radical generation during ischemia and reperfusion.
It has been suggested that oxygen-derived free radicals may contribute to the myocardial injury associated with ischemia and reperfusion. As the presence of enhanced free radical generation is a prerequisite for such damage, several techniques have been used to provide evidence of increased oxygen free radical production during reperfusion; however, all such techniques have substantial limitati...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 1986
ISSN: 0022-5223
DOI: 10.1016/s0022-5223(19)36094-5